The Headquarters (HDQ) Troop Investigative Services Division of the Nebraska State Patrol includes three areas of concentration, drug investigation, criminal investigation and liquor enforcement. The Investigative Services Division in HDQ Troop is comprised of one Lieutenant, three Sergeants and 14 Investigators.

The HDQ Investigative Services Criminal Investigators work cases ranging from theft to homicides.

The HDQ Troop Drug Division currently has the task force, Mid & Upper Level Enforcement (MULE).  HDQ investigators play an integral part in this task force comprised of city, county and federal investigators, analysts and prosecutors working to stop the sale and distribution of illegal drugs.

The HDQ Liquor Division monitors licensed liquor establishments to verify that they are in compliance with the State's Liquor laws.  Enforcement of the laws pertaining to gaming, tobacco and underage drinking are also a part of this division's duties.